@masterthesis{Breher2015, type = {Bachelor Thesis}, author = {Breher, Katharina}, title = {Visual consequences of Albinism}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-1939}, school = {Hochschule Aalen}, pages = {83 Seiten}, year = {2015}, abstract = {Purpose: The purpose of this thesis is to provide a comprehensive literature review about albinism as an inherited metabolic disorder of melanin synthesis along with those related conditions impacting the visual system. As such, it addresses eye care emphasizing the visual consequences of albinism along with diagnostic and treatment options. Methods: Background knowledge about ocular development is given as well as information about etiological biochemical and genetic processes. The current classification, clinical findings and their assessment and management options are presented based on recent results of research. In conclusion, two case reports are described as examples of visual care options. Results: Melanin plays a big role in the retinal and chiasmal development. Melanin biosynthesis can be disrupted by different genes in various ways which leads to the current classification of albinism. Clinical findings include fundus hypopigmenta-tion, nystagmus, iris transillumination, photophobia, foveal hypoplasia, excessive chiasmal decussation, reduced visual acuity, high astigmatism (with-the-rule), strabismus and decreased stereopsis. Treatment options to improve visual acuity, fixation and binocularity are (tinted) prescription lenses and contact lenses, low vision aids, surgical procedures and vision therapy. Medication and supplementa-tion for increased pigmentation are currently being tested on mice. Conclusions: Albinism is caused by genetic mutations resulting in ocular and cutaneous hypopigmentation. It establishes various phenotypes that require different therapy approaches in order to improve vision and therefore quality of life.}, language = {en} } @masterthesis{Hahn2014, type = {Bachelor Thesis}, author = {Hahn, Benjamin}, title = {Validation of a measuring device constructed on bases of the principle of the center of rotation of the eye}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-1417}, school = {Hochschule Aalen}, pages = {V, 60 S.}, year = {2014}, abstract = {Ophthalmic lenses are ideally measured in accordance with the center of rotation of the eye. Therefore a measuring device was constructed due to this principle to measure lenses with a focimeter. In this work that measuring device was validated. Lenses of ± 4 dpt in spherical and aspherical design were measured across a field of 9x9 measuring points being at 5° distance from each other. This corresponds to a field of view of 40°. The measurement points in x- and y- direction were theoretically calculated to validate the measurement results. Regarding angles of incidence up to 20° it was supposed that the main optical aberration depends on a change in the sagittal and tangential sphere powers which is also defined as astigmatism. Therefore the calculation presents the tangential and sagittal oblique sphere powers depending on the different angles of the line of vision. On average the measurement results and the calculated data of the spherical designed lenses coincide quite good (correlation at 0,98), the systematic deviation of both values on average is 0.01 dpt and the random error (standard deviation) amounts 0.03 dpt on average. The minimum deviation is -0.06 dpt and the maximum is 0.09 dpt. Common focimeters have a measuring inaccuracy of up to 0.06 dpt (Diepes, Blendowske 2002). Therefore the quality of the measured data should be reliable. The aspherical designed lenses were compared to the spherical designed lenses. With increased angles of incidence the astigmatism of the aspherical lenses leads to lower values than the astigmatism of the spherical lenses}, language = {en} } @misc{Karmis2020, type = {Master Thesis}, author = {Karmis, Marios}, title = {The use of the direct ophthalmoscope in a "modern" practice and the development of a more digitalized ophthalmoscope as a project}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-9725}, pages = {xliii, viii}, year = {2020}, abstract = {The direct ophthalmoscope is a retinal screening tool that has been in existence and development for more than 150 years, yet, the rapid influence of technological evolution in screening tools, has left the direct ophthalmoscope untouched. The main purpose of this master thesis is to determine if the direct ophthalmoscope has reached its maximum potential of development and, additionally, to determine if a further development, including a more electronic input, would be feasible.}, language = {en} } @misc{Breher2018, type = {Master Thesis}, author = {Breher, Katharina}, title = {The effect of the optical design of multifocal contact lenses on choroidal thickness}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-6800}, pages = {XXXV, 29 Seiten}, year = {2018}, abstract = {Purpose: Recent studies found a reduction of myopia progression with multifocal contact lenses, however, with yet unclear mechanism. This raises the hypothesis that the addition zones of the multifocal contact lenses induce myopic defocus on the retina, which consequentially leads to choroidal thickening and therefore inhibited eye growth. We tested the effect of the optical design of multifocal contact lenses on choroidal thickness. Methods: 18 myopic students wore four different contact lenses ((1) single-vision lens corrected for distance, (2) single-vision lens with +2.50 D full-field defocus, (3) "Multifocal center-distance" design, addition +2.50 D, (4) "Multifocal center-near" design, addition +2.50 D) for each 30 minutes on their right eye. Automated analysis of the macular choroidal thickness, vitreous chamber depth and eccentric photorefraction were performed before and after each contact lens. Results: Choroidal thickness and vitreous chamber depth showed no significant differences to baseline with none of the contact lenses. Choroidal thickness increased the most with the "Multifocal center-distance" and the full-field defocus lens, followed by the "Multifocal center-near" and the single-vision contact lens (+2.1 ± 11.1 μm, +2.0 ± 11.1 μm, +1.6 ± 11.3 μm, +0.9 ± 11.2 μm, respectively). The "Multifocal center-distance" design showed an overall more myopic refractive profile than the other lenses. Changes of vitreous chamber depth occurred in anti-phase to these of choroidal thickness. Conclusion: Multifocal contact lenses have no significant influence on choroidal thickness and after short-term wear. Therefore, it is assumed that it is not the main contributor to the protective effect of multifocal contact lenses in myopia control.}, language = {en} } @misc{Smuglova2020, type = {Master Thesis}, author = {Smuglova, Ekaterina}, title = {Prevalence of vision disorders among school-aged children in Russia}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-9705}, school = {Hochschule Aalen}, pages = {XVII, 21}, year = {2020}, abstract = {This research project is of particular importance since there is a lack of adequate data on pediatric eye and vision disorders in Russia, particularly in the Volga region. In the present study, we estimate the prevalence of vision disorders among school-aged children who participated in a vision screening program in Samara, Russia. The relationship between learning-related visual dysfunctions is explored in depth, such to illustrate the connection between vision and learning. Hence, a key feature in this study is the inclusion of binocular vision disorders among the conditions tested.}, language = {en} } @misc{Mattern2020, type = {Master Thesis}, author = {Mattern, Ann-Isabel Britta}, title = {Low-Level Neural Processing of Photoreceptor Neuron Signals}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-9959}, school = {Hochschule Aalen}, pages = {xv, 37 Seiten}, year = {2020}, abstract = {Novel myopia control spectacle lenses induce peripheral contrast reduction via optical diffusion. It is suggested, that the contrast reduction alters retinal processes in the low-level neural circuity, leading to an inhibition of eye growth. The purpose of this thesis is to evaluate the influence of full-field contrast reduction on low-level neural processing of the retina, described by the edge contrast sensitivity.}, language = {en} } @masterthesis{Bandle2019, type = {Bachelor Thesis}, author = {Bandle, Dorothee}, title = {Keratoconus Indices Indicative of Progression using the Pentacam HR®}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-9975}, school = {Hochschule Aalen}, pages = {XVI, 47}, year = {2019}, abstract = {The Purpose of this thesis is to determine the indices of the Pentacam HR® which change enough in longitudinal data to detect and predict Keratoconus progression and how they correlate to demographic/other predictor variables.}, language = {en} } @misc{vonderHeide2019, type = {Master Thesis}, author = {von der Heide, Andreas}, title = {Fitting Soft Multifocal Customized Contact Lenses for Myopia Control}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-6837}, pages = {LXXIV, 130 Seiten}, year = {2019}, abstract = {The increasing prevalence of myopia throughout the industrialized world in recent decades has caused costs and problems for the eye health. Changed lifestyle and behavior are the main causes. For the pathogenesis of myopia, the amount of time spent outdoor and near activities play an important role. Various options for the treatment of myopia have been described as effective in the literature. Normal single vision glasses and contact lenses can only provide clear vision, but do not reduce myopia progression. Orthokeratology shows a slowing of axial growth, but has an increased risk of infectious keratitis. Low-dose atropine (0.01\%) is currently the best pharmacological option. It proved safe, effective and showed the least rebound effect with negligible side effects. Other options for the treatment of myopia include special glasses, behavioral changes and prolonged outdoor exposure (to prevent the onset of myopia), as well as other methods. An increasingly important myopia management option is multifocal contact lenses, that provide a peripheral treatment zone producing myopic defocus. Such myopia control lenses are available as customized or as daily or monthly lenses. Children benefit from wearing contact lenses more than just having refractive error correction and myopia control, they have a better self-esteem and improved quality of life. The numerous findings on the safety and efficacy of soft multifocal distance center contact lenses in children to reduce the progression of myopia suggest that this modality should be considered as a main treatment option. Less, but similar to orthokeratology, when wearing soft lenses there is a risk of developing potentially serious complications such as microbial keratitis. The introduction of child-appropriate risk minimization strategies, and patient and parent education with regular monitoring is essential and leads to successful contact lens wear. This literature review summarized the actual knowledge about myopia management, prevalence, etiology and the visual and healthy consequences of myopia. The three currently most important strategies for slowing the progression of myopia are soft multifocal distance center contact lenses, Orthokeratology and low-dose atropine ophthalmic drops.}, language = {en} } @misc{Rothe2015, type = {Master Thesis}, author = {Rothe, Colleen}, title = {Evaluation of Scanpath Comparison Metrics for Static and Dynamic Tasks}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-1633}, school = {Hochschule Aalen}, year = {2015}, abstract = {Purpose Automated scanpath comparison metrics should deliver an objective method to evaluate the similarity of scanpaths. The aim of this thesis is an evaluation of seven existing scanpath comparison metrics in static and dynamic tasks in order to provide a guidline that helps to decide which algorithm has to be chosen for a special kind of task. Methods The applicability of the algorithms for a static, visual search task and a dynamic, interactive video game task as well as their constraints and limitations were tested. Therefore, binocular gaze data were recorded by using the eye tracking system The Eye Tribe (The Eye Tribe ApS, Copenhagen/ Denmark). Objective task performance measures from 21 subjects were used in order to create scanpath groupings for which a relevant effect of dissimilarity was to be expected. Objective task performance measures such as task performance time were statistically evaluated and compared to the results gained by the comparison metrics. Results Four of the algorithms being used successfully identified differences for static and dynamic tasks: MultiMatch, iComp, SubsMatch and the Hidden Markov Model. ScanMatch was very sensitive for the static task but not applicable to the dynamic task whereas FuncSim was suitable for dynamic but not for static tasks. Eyenalysis failed to detect any effect. Conclusion The applicability of scanpath comparison metrics depends on the state of the task, respectively on the kind of experimental set up. In future, the application area for eye tracking will expand and an improvement of automated scanpath comparison metrics is therefore required.}, subject = {Mustererkennung}, language = {en} } @masterthesis{Frisch2016, type = {Bachelor Thesis}, author = {Frisch, Jasmina}, title = {Determination of stereoacuity thresholds and their inherent test retest reliabilities at various eccentricities with a monitor-based two-rod-test}, url = {http://nbn-resolving.de/urn:nbn:de:bsz:944-opus4-1942}, school = {Hochschule Aalen}, pages = {46 Seiten, XXXI}, year = {2016}, abstract = {Ziel Ziel der Studie ist es, mit einem zwei St{\"a}bchen Test am Monitor, die Schwellenwertbestimmung an verschiedenen Exzentrizit{\"a}ten des binokularen Gesichtsfeldes und deren Wiederholbarkeit durchzuf{\"u}hren. Weiter soll die Dauer der einzelnen Messungen festgehalten und ausgewertet werden. Methode Die Explorative Studie wurde mit f{\"u}nf Probanden im Alter von 21 bis 23 Jahren (2 m{\"a}nnlich und 3 weiblich) durchgef{\"u}hrt. Zwei schwarze Balken auf weißem Hintergrund, welche unter einem Winkel von 1° bei einer Beobachtungsentfernung von 5.0 Metern erscheinen, bildeten das Stereobild. Der rechte Balken diente als ortsfester Vergleichsbalken, w{\"a}hrend der linke Balken zu beurteilen war und durch die stereoskopische Parallaxe, entweder nach vorne oder hinten versetzt erschien. Die Schwellenwertbestimmung erfolgte in sieben Exzentrizit{\"a}ten zu beiden Seiten des Gesichtsfeldes (0° zentral, 5° rechts/links, 10° rechts/links und 15° rechts/links). Die Darbietung und Abfolge der Bilder mit proximalen und distalen Verschiebungen in den verschiedenen Exzentrizit{\"a}ten erfolgte randomisiert. Die Bestimmung der Grenzwinkel wurde f{\"u}r 4 Probanden in zwei Sitzungen und f{\"u}r 1 Proband in f{\"u}nf Sitzungen durchgef{\"u}hrt, wovon bei jeder die Zeit festgehalten wurde. Alle Sitzungen waren mindestens 24 Stunden und l{\"a}ngstens 7 Tage voneinander getrennt. Die Auswertung erfolgte durch das bilden von Median und den statistischen Tests von Wilcoxon und Kruskal Wallis mit einem 95\% Konfidenzintervall (CI). Ergebnisse Peripheres Stereosehen verl{\"a}uft {\"a}hnlich abfallend zur Sehsch{\"a}rfe. W{\"a}hrend zentral kleinste proximale Winkel von median 5.0 Winkelsekunden ('') und einem CI (0.5'',30.5'') gefunden wurden, stiegen diese auf 112.2'' in 15° Exzentrizit{\"a}t nach links bei proximaler Darbietung. Distal waren es 19.9'' zentral und 112.2'' in 15° nach rechts. Die Wiederholbarkeit der Grenzwinkelbestimmung war zentral und proximal am genauesten, w{\"a}hrend in 15° nach links und distal die schlechteste Wiederholbarkeit entdeckt wurde. Zwischen den einzelnen Messungen wurden signifikante Unterschiede der Messdauer gefunden. Die Messdauer liegt bei 5.3 (3.2, 8.3) Minuten. Schlussfolgerung Stereogrenzwinkel weichen bei Wiederholungen nicht stark voneinander ab. Mit zunehmender Exzentrizit{\"a}t nehmen die Grenzwinkel zu. Durch die Dauer der Messungen, erscheint der zwei St{\"a}bchen Test am Monitor als schnelle Messmethode die f{\"u}r zuk{\"u}nftige Studien hergenommen werden kann. Jedoch ist der Algorithmus, wie auch die Stereoskopischen Bilder fehlerhaft und sollte {\"u}berarbeitet werden.}, language = {en} }